A Shot of Science

Vaccines are among the most significant achievements in public health. Since 1924, childhood vaccinations have prevented more than 100 million cases of serious disease.

All vaccines used in the US are required to go through extensive safety testing before they are licensed by the US Food and Drug Administration (FDA) or recommended for widespread use.

After a vaccine is licensed, FDA and the Centers for Disease Control and Prevention (CDC) work with healthcare professionals to monitor the safety of vaccines, including any adverse events, especially rare events not identified in pre-licensure study trials. There are four systems in place in the US to monitor the safety of vaccines after they are licensed and used among the public, and new systems have been established to help monitor vaccines for COVID-19. These systems can monitor known side effects and detect rare side effects that may not have been identified during clinical trials.

One of the systems used to monitor the post-licensure safety of vaccines in the US is the Vaccine Adverse Event Reporting System (VAERS). VAERS accepts reports from healthcare professionals, vaccine manufacturers, and the general public and receives more than 25,000 reports per year, compared with millions of vaccine doses administered.

#ShotOfScience Campaign

NFID developed a #ShotOfScience campaign to share tools and resources on the history and science of vaccines. Campaign materials include sample social media posts and animated graphics.

Vaccine Safety Infographic
Graphic

Vaccine Safety Infographic

Infographic detailing science and safety of vaccines

Learn More
Shot of Science
Graphic

Vaccine Science Social Media Toolkit

Sharable social posts on vaccine safety

Learn More
A graphic outlining the history of vaccines
Graphic

A Shot of Science: Brief History of Vaccine Accomplishments

Infographic detailing the history and timeline of vaccine development

Learn More

For more information about how vaccines are developed, approved, manufactured, and added to the US Recommended Immunization Schedule, view the CDC infographic, The Journey of Your Child’s Vaccine.

The National Academies of Sciences, Engineering, and Medicine has also compiled extensive information about vaccine safety.

 

Updated May 2022

Sources: Centers for Disease Control and Prevention, Department of Health and Human Services, National Academies of Sciences, Engineering, and Medicine

Related Resources

How antibiotic resistance spreads
March 21, 2016

National Patient Safety Week: Focus on Antimicrobial Resistance

With a focus on increasing awareness of patient safety among healthcare professionals and consumers, National Patient Safety Awareness Week provides an opportunity to highlight an issue that affects more than 700,000 patients each year—healthcare-associated infections.

Learn More
Vaccine Safety
July 21, 2015

Vaccine Safety: What You Should Know

The independent and multi-layered vaccine review process can be complicated but is in place to ensure that vaccines are held to the highest standards of safety. Moreover, continuous monitoring of health problems after vaccination ensures that the US has a safe and effective vaccine supply.

Learn More