Render of HIV/AIDS

What is HIV/AIDS?

HIV is a virus that can be transmitted through sexual contact and can also be spread by contact with infected blood or from mother to child during pregnancy, childbirth, or breast-feeding. Without medication, HIV gradually weakens the immune system to the point that an infected individual may develop acquired immunodeficiency syndrome (AIDS).

AIDS is a chronic, potentially life-threatening condition caused by HIV infection. By damaging the immune system, HIV interferes with the body’s ability to fight the organisms that cause disease.


Approximately 1.2 million people in the US are living with HIV today. About 13% of them are unaware they are infected. An estimated 30,000+ people became newly infected with HIV in the US each year.


HIV infection happens in three stages. Without treatment, it gets worse over time and eventually overpowers the immune system. Symptoms depend on the stage (Acute, Clinical Latency, AIDS) and may include:

  • Chills
  • Fatigue
  • Fever
  • Muscle aches
  • Mouth sores
  • Night sweats
  • Rash
  • Sore throat
  • Swollen lymph nodes

Some people have no symptoms at all and the only way to know if you have HIV is to get tested.


Various strategies are available to prevent HIV including correctly using condoms during sex, limiting the number of sexual partners, never sharing needles, and abstinence (not having sex). Individuals who are at risk for HIV can protect themselves through pre-exposure prophylaxis (PrEP)—taking daily antiretroviral medicines (ART) before being exposed to the HIV virus. Individuals who think they may have been exposed to HIV should talk to a healthcare professional about post-exposure prophylaxis (PEP)—taking ART after being exposed to prevent becoming infected.

If you have HIV, there are actions you can take to avoid transmitting it to others. The most important is taking HIV medicine (ART) as prescribed. If you take HIV medicine as prescribed and stay virally suppressed, you can stay healthy and have effectively no risk of transmitting HIV to an HIV-negative sex partner.

The Centers for Disease Control and Prevention (CDC) recommends that everyone between the ages of 13 and 64 years get tested for HIV at least once in their lifetime as part of routine healthcare, and more often for those at increased risk for getting HIV.


There is currently no cure for HIV/AIDS, but there are medications that can slow the progression of the disease. These drugs have reduced AIDS deaths in many developed nations.

Updated March 2023

Source: Centers for Disease Control and Prevention

Related Resources

Seth Berkley Infectious Ideas Podcase Episode 11, Season 2

A Leader for Global Health Equity—Seth F. Berkley, MD

S2, E11: Seth F. Berkley, MD, shares insights from his notable career, including his impactful work in Uganda rebuilding the immunization program and developing the national AIDS control program, his work with Gavi, the Vaccine Alliance, and his trailblazing leadership of COVAX, which helped deliver more than 2 billion doses of COVID-19 vaccines globally to 146 countries.

Learn More
From HIV/AIDs to COVID-19: Insights and Predictions

From HIV/AIDs to COVID-19: Insights and Predictions with Rochelle P. Walensky, MD, MPH

S2, E2: Rochelle P. Walensky, MD, MPH, shares her perspectives on the most significant changes she has seen throughout her career, the importance of rebuilding trust in government agencies, and predictions for the upcoming respiratory season …

Learn More