In the US, all vaccines must be approved or licensed by the Food and Drug Administration (FDA), after which every vaccine is continually evaluated for safety and efficacy. This site reflects evidence-based US immunization recommendations.

Recommendations by Age
Evidence-based immunization schedule for infants and children from the American Academy of Pediatrics (AAP)
Evidence-based immunization schedule for adults based on age and medical conditions from the American Academy of Family Physicians (AAFP)
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4 Ways to Address Disparities in Vaccination Rates
Despite overwhelming evidence of the benefits of vaccination against many diseases, immunization rates have historically been low among communities of color …
Data-Driven Approach to Increasing US Vaccine Uptake
The goal of the pilot project is to assist those on the frontlines in deploying effective approaches to public health outreach and service delivery.
5 Things to Know about Infant Immunization
Immunization is one of the most effective ways to help protect infants from serious diseases
Updated August 2025
Sources: American Academy of Pediatrics, American Academy of Family Physicians