In a year marked by the re-emergence of old threats and a rising tide of public health mis- and disinformation, the National Foundation for Infectious Diseases (NFID) remained a steadfast voice for science and evidence-based guidance. As we look back on 2025, the numbers tell a story of resilience, innovation, and the critical support provided during this time.
Here are some highlights of what NFID accomplished in 2025, by the numbers …
The Digital Front Line: Innovation in Action
To overcome confusion and provide timely, trusted answers, NFID used technology to reach people where they are.
- Ask MERL: Launched as a new AI-powered search tool to help the public and healthcare professionals find trusted, science-based NFID resources instantly
- US Adult Vaccine Uptake Dashboard: Collaborated with partners to develop a new hyperlocal data tool to help public health leaders identify barriers to vaccination in their communities
The Toll of Declining Rates
The numbers remind us why NFID’s mission is more critical than ever. When vaccination rates fall, the human and economic costs are staggering.
- 2,144: US measles cases in 2025—the highest number since 2000
- 289: Pediatric flu-related deaths during the high-severity 2024-2025 respiratory season
- $7+ Billion: The annual economic burden of vaccine-preventable diseases in the US, with unvaccinated individuals accounting for nearly 80% of these costs
- 25%: Of US adults surveyed by NFID reported they could not access COVID-19 vaccines in their local area
Mobilizing for Truth
NFID didn’t just report on the news; we led the response to protect public health and increase awareness of the burden, prevention, and treatment of infectious diseases.
- 8.58+ Billion: Campaign impressions for the 2025-2026 respiratory season outreach
- 1.7 Billion: Media impressions for the Hands In For Handwashing campaign
- 330+ Organizations: Now part of the NFID partnership network, working toward the shared vision of healthier lives for all
- 20+ Advocacy Letters: Endorsed by NFID in 2025 to uphold scientific integrity in US immunization policy
Empowering the Experts
We continue to support healthcare professionals on the front lines of patient care.
- 8,000+ Individuals: From 86 countries participated in NFID professional educational activities
- 20 Education Activities: Hosted webinars, courses, and conferences to translate critical information into practical guidance for the medical community
2025 was a difficult and dangerous year for public health. … In a year marked by uncertainty, NFID worked to break through the noise and provide reliable, evidence-based guidance, embracing our role as a convener of organizations whose collective action will be essential in the years ahead.
NFID President Jeffery A. Goad, PharmD, MPH and NFID CEO Rebecca Alvania, PhD, MA, MPH
Invest in a Healthier Future
While 2025 was a challenging year, it was also one of progress. As we prepare to launch a new strategic plan in 2026, we remain focused on expanding our reach and deepening our partnerships to meet the urgency of this moment. Help us continue this work. Donate to NFID today to invest in a healthier, more resilient future. Visit www.nfid.org/support to learn more and make an online donation.
From all of us at NFID, thank you for your continued support! We wish you the gift of health throughout the coming year …
To join the conversation and get the latest news on infectious diseases:
- Like and follow NFID on social media
- Listen and subscribe to the Infectious IDeas podcast
- Subscribe to receive future NFID Updates
