Second Annual Conference on Vaccine Research (1999)

Philip K. Russell, MD
The Johns Hopkins University School of Hygiene and Public Health

• SEROPROTECTIVE LEVELS AGAINST LYME DISEASE ACHIEVED AFTER IMMUNIZATION WITH LYMERIX LYME DISEASE VACCINE (RECOMBINANT OspA) - D. L. Parenti
• A SINGLE BLINDED RANDOMISED TRIAL COMPARING TWO ADULT ACELLULAR PERTUSSIS VACCINES WITH A LICENSED ADULT DIPHTHERIA-TETANUS VACCINE (ADT) - F.M. Tumbull
• NASOPHARYNGEAL CARRIAGE OF STREPTOCOCCUS PNEUMONIAE IN INFANTS GIVEN PRIMARY AND BOOSTER DOSES OF 7 -VALENT PNEUMOCCOCAL CONJUGATE VACCINE - S. Yeh
• RECOMBINANT POLYVALENT VACCINE AGAINST MELIODOSIS AND GLANDERS - N.N. Kislichkin
• TOWARDS A VACCNE FOR SHIGA TOXIN-PRODUCING E. COLI (STEC): PROTECTION AGAINST HEMORRAGIC COLITIS IN AN ANIMAL MODEL BY IMMUNIZATION WITH A RABBIT ENTEROPATHOGENIC E. COLI (REPEC) EXPRESSING TRUNCATED INTIMIN - T. Agin
• STUDY OF A NASAL VACCINE AGAINST NEISSERIA MENINGITIDIS B IN A MOUSE MODEL - E.N. De Gaspari

• TOPICAL APPLICATION OF ANTIGEN TO THE SKIN SURFACE RAPIDLY INDUCES ANTIGEN SPECIFIC CD4+ T CELL RESPONSES - T.M. Scharton-Kersten
• DEVELOPMENT OF AN EDIBLE VACCINE TO SWINE TRANSMISSIBLE GASTROENTERITIS VIRUS USING ANTIGENS EXPRESSED IN MAIZE SEED - Joseph M. Jilka
• CELLULAR SELECTION OF HUMAN ROTATAVIRUS ENTEROTOXIN GENE VARIANTS IN CELL CULTURE: A POTENTIAL STRATEGY TO OBTAIN NONTOXIC FORMS OF TOXIC GENES FOR SUBUNIT VACCINE APPLICATIONS - C.D. Atreya
• BOTH ANTIBODY-DEPENDENT AND -INDEPENDENT PROTECTION ARE STIMULATED AFTER INTRANASAL IMMUNIZATION OF MICE WITH INACTIVATED ROTAVIRUS PARTICLES - R.L. Ward
• A NEW VACCINE STRATEGY: ENHANCEMENT OF T CELL RESPONSES BY RECRUITING CD26 TO THE TCR/MHC COMPLEX WITH A HIGH-AFFINITY CD26 LIGAND COVALENTLYATTACHED TO COGNATE T CELL PEPTIDE EPITOPES - C. Plant
• STRATEGY FOR ISOLATION OF MEASLES VACCINE VIRUS (MRV) PROCESSED PEPTIDES FROM CLASS II HLA-DR4 ALLELES - I.G. Ovsyannikova

• BIVALENT ENVELOPE VACCINES (AIDSVAX™) EVALUATED FOR EFFICACY AGAINST BLOOD-BORNE ANO SEXUALLY TRANSMITTED HIV-1 IN THAILAND AND NORTH AMERICA - D.P. Francis
• TESTING TETRAVALENT LIVE-ATTENUATED DENGUE VACCINE CANDIDATES IN HUMAN SUBJECTS BY FACTORIAL DESIGN - W. Sun
• EVALUATION OF THE SAFETY, IMMUNOGENICITY, AND VIRUS SHEDDING OF A INTRANASAL BOVINE PARAINFLUENZA VIRUS TYPE 3 (PIV3) VACCINE IN INFANTS - P. Greenberg
• PHASE I SAFETY AND IMMUNOGENICITY TRIAL OF A RECOMBINANT HEPATITIS E VIRUS VACCINE - R. Kuschner

• CHIMERIVAX - NOVEL, LIVE ATTENUATED GENETICALLY-ENGINEERED VACCINES AGAINST HETEROLOGOUS FLAVIVIRUSES, BASED ON YELLOW FEVER (YF) 17D VACCINE - T.P. Monath
• EFFECTIVENESS OF INACTIVATED HANTAAN VIRUS VACCINE (HANTAVAX) AGAINST HEMORRHAGIC FEVER WITH RENAL SYNDROME: A POPULATION-BASED, CASE-CONTROL STUDY IN KOREAN SOLDIERS - You-Choel Shin
• BOOSTER DOSES OF MEASLES VACCINE IN SCHOOLCHILDREN: RESPONSES TO DIFFERENT VACCINE STRAINS AND THE AEROSAL ROUTE - A. Dilraj
• REACTOGENICITY AND IMMUNOGENICITY OF COMBINED MEASLES-MUMPS-RUBELIA-VARICELLAA VACCINE, AND MEASLES-MUMPS-RUBELLA VACCINE ALONE OR WIIH VARICELLA VACCINE AS A SINGLE INJECTION EXTEMPORANEOUS MIX - T. Nolan
• ENHANCE HUMORAL RESPONSES TO HCV ENVELOPE IN DNA IMMUNIZATION BY PROTEIN BOOST - Guo-Jun Hu
• REVISITING WHOLE-INACTlVATED HIV-1VACCINES: RETENTION OF GPl20 AND ENHANCED ANTIGENICITY OF CONFORMATION-DEPENDENT NEUTRALIZATION EPITOPES - K. Grovit-Ferbas

• GELATIN IN VACCINES AS A POSSIBLE CAUSE OF ANAPHYLAXIS - V. Pool
• THE SAFETY OF HEPATITIS B VACCINE IN ADULTS - R. Chen
• CLINICAL STUDIES OF THE TOLERANCE OF INTRAMUSCULAR QS-21 FORMULATIONS - C. Kensil
• DOES INFLUENZA VACCINATION PROTECT CHILDREN AGAINST EXACERBATION OF ASTHMA? - P. Kramarz
• IS IT IMMUNOLOGICALLY FEASIBLE TO DELAY ADULT DIPHTHERIA/TETANUS BOOSTER IMMUNIZATION TO AGE 50? - David W. ScheifeIe
• BIOSYNTHETIC MODIFICATION OF A LIPID-A ASSOCIATED TOXICITY AND ADJUVANT ACTIVITY IN NEISSERIA MENINGITIDIS: IMPLICATIONS FOR VACCINE DEVELOPMENT - Peter van der Ley

• DIFFERENTIAL INDUCTION OF IL-8 AND MIP1-BETA BY BCG - C. Jagannath
• CLONING, EXPRESSION, AND IMMUNE RESPONSES T0 THE 65 KILODALTON HEAT SHOCK PROTElN OF M. AVIUM - M. .V. Nagabhushanam
• A LARGE COMMUNITY TRIAL TD EVALUATE THE EFFICACY OF A SECOND BCG DOSE IN SCHOOLCHILDREN AGAINST TUBERCULOSIS AND LEPROSY IN BRAZIL - Mauricio L. Barreto
• A NASAL VACCINE INDUCED BETTER ANTIBODY RESPONSES WHEN GIVEN AS REPEATED SMALL DOSES RATHER THAN AS ONE SINGLE LARGE DOSE - B. Haneberg
• A NASAL OUTER MEMBRANE VESICLE (OMV) VACCINE CAN INDUCE IMMUNOLOGICAL MEMORY WITH STRONG BOOSTER ANTIBODY RESPONSES - B. Haneberg
• IDENTIFICATION OF A NOVEL OUTER MEMBRANE PROTEIN OF NEISSERIA MENINGITIDIS AND ITS POTENTIAL AS A VACCINE CANDIDATE - L.M.C. Coutinho
• TRIVALENT SHIGELLAE LIPOPOLYSACCHARIDE VACCINE - P.G. Aparin
• INVESTIGATION OF CELLULAR AND HUMORAL IMMUNE RESPONSES TO WHOLE CELL AND ACELLULAR PERTUSSIS VACCINES - Catpagavalli Canthaboo
• B CELL EFFECTOR RESPONSES IN THE GASTRIC ANTRUM AND DUODENUM FOLLOWING HELIOCOBACTER PYLORI ADJUVANTED WITH LTR192G IN H. PYLORI SERONEGATIVE (HP-) INDlVIDUALS - G.A. Losonsky
• DEVELOPMENT OF A DNA VACCINE AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) - J.P. Senna
• INVASIVE PNEUMOCOCCAL INFECTIONS IN CANADIAN CHILDREN, 1991-8: IMPLICATIONS FOR NEW VACCINATION STRATEGIES - David W. Scheife1e,
• DIPHTHERIA AND POLIOMYELITIS IMMUNITY IN THE NETHERLANDS - H.E. de Melker
• RE-VACCINATING CHILDREN PREVIOUSLY VACCINATED WITH EDMONSTON-ZAGREB (EZ) MEASLES VACCINE - M. Khalil
• EXPRESSION OF THE RECOMBINANT DENGUE 4 VIRUS TRUNCATED E GLYCOPROTElN MADE IN PICHIA PASTORIS AND EVALUATION OF THE IMMUNE RESPONSE INDUCED IN MICE - R. Rodriguez
• EXPRESSION OF TRUNCATED DENGUE-2 PROTEIN BY A DNA VACCINE CANDIDATE IS DEPENDENT OF ITS SIGNAL PEPTIDE BUT INDEPENDENT OF THE WHOLE PRM PROTEIN - R. Occazionez
• DENGUE-2 DNA VACCINE CANDIDATE EXPRESSING A TRUNCATED E PROTEIN PROLONGS ITS MICE SURVIVAL AFTER CHALLENGE WITH A VIRULENT STRAIN - R. Occazionez
• ATYPICAL IMMUNE RESPONSES AMONG DENGUE VACCINE RECIPIENTS ATTRIBUTABLE TO OCCULT YELLOW FEVER EXPOSURE - N. Kanesa-thasan
• HIGH AVIDITY VIRUS SPECIFIC-IGG ANTIBODY RESPONSE AFTER INAVTIVATED HANTAAN VIRUS VACCINE IMMUNIZATION AND ITS UTILITY - Min-Ja Kim
• SAFETY AND IMMUNOGENICITY OF A LIVE-ATTENUATED, MUTAGENIZED RIFT VALLEY FEVER VACCINE IN HUMANS - P.R. Pittman
• DEVELOPMENT OF DNA VACCINES DIRECTING ANTIGENS TO ALTERNATIVE CELLULAR PROCESSING PATHWAYS AND THEIR EFFECT ON THE IMMUNE RESPONSE - S. Cohen
• NUCLEIC ACID VACCINATION AGAINST HEPATITIS B SURFACE ANTIGEN IN MICE - A. Karami
• THE ATTENUATION PHENOTYPE OF LIVE, TEMPERATURE-SENSITIVE (TS) VACCINE STRAINS AT RESTRICTIVE TEMPERATURES IS NOT ASSOCIATED WITH ENHANCED INTERFERON SYNTHESIS OR INCREASED-SENSITIVITY TO TYPE 1 INTERFERONS (IFNS) - D.A. Loveys
• RESTRICTED REPLICATION OF A CHIMERIC VIRUS FOR INDUCING PROTECT IMMUNITY AGAINST SIV INFECTION - T. Matano
• ALTERED PATTERNS OF SIVMAC251 INFECTION AFTER DNA VACCINATION IN MACAQUES - Pbilippe Lena
• THE CYTOPLASMIC TAIL OF CD86 COSTIMULATORY MOLECULE INVOLVED IN ANTI-HIV CTL RESPONSES DURING DNA VACCINATION - B. Monzavi-Karbassi
• EFFECT OF PROMOTER STRENGTH ON CELLULAR AND HUMORAL IMMUNE RESPONSES ELICITED BY HIV-l MULTIGENIC DNA VACCINES - T.A. Galvin
• HUMORAL AND CELLULAR IMMUNE RESPONSE ELICITED BY HIV-ENV DNA CONSTRUCTS IN MICE - Alka Arora
• HIV-1 VACCINE TRIALS AT THE VACCINE TRIAL CENTRE (VTC) IN BANGKOK - Punnee Pitisuttihum
• INCREASING HIV INCIDENCE IN A HIGH RISK HETEROSEXUAL POPULATION SUITABLE FOR VACCINE TRIALS IN HONDURAS - W. Kiaskala
• THE INFLUENCE OF CHANGES IN KNOWLEDGE OF VACCINE TRIAL CONCEPTS ON WILLINGNESS TO PARTICIPATE IN VACCINE TRIALS OVER 18 MONTHS FOLLOW-UP IN THE VACCINE PREPAREDNESS STUDY OF THE HIVNET - W.R. Lenderking
• FEASIBILITY OF EFFICACY TRIALS ON HIV VACCINES: COHORT BELA VISTA - Jose R. Carvalheiro
• CLINICAL TRIALS WITH CANDIDATE HIV/AIDS VACCINES IN BRAZIL - Jose R. Carvalheiro
• RESULTS OF A HIV INCIDENCE COHORT OF HOMO/BISEXUAL MEN IN PREPARATION FOR FUTURE CLINICAL TRIALS IN BALA HORIZONTE, BRAZIL - 4 TEAR REPORT OF THE PROJECT HORIZONTE
• HIV VACCINES CLINICAL TRIALS IN "DEVELOPING" COUNTRIES: THE FALLACY OF URGENCY OR ETHICS VS. ECONOMICS - Dirceu B. Greco
• IMMUNIZATION OF BALBC MICE WITH A PLASMID CODING FOR A HYBRID MSP1.19-HBSAG PROTEIN INDUCES PARTIAL PROTECTION AGAINST LETHAL P. CHABAUDI MALARIA BLOOD STAGE INFECTION - G. Wunderlich
• MOUSE MODEL FOR GENITAL TRACT ASCENDING INFECTION BY CHLAMYDIA TRACHOMATIS SEROVAR D AND ASSESMENT BY DNA VACCINATION - R. Cevenini
• DEVELOPMENT OF A VACCINE AGAINST COCCIDIOIDOMYCOSIS - G.W. Rutherford
• PROTEIN AGAINST BOVINE VIRAL DIARRHEA VIRUS (BVDV) OF CALVES VACCINATED WITH A BOVINE HERPESVIRUS-l (BHV.l ).BVDV RECOMBINANT - H. J. Swan
• INVESTIGATION OF THE PROTECTIVE CAPACITY OF COMMERCIAL VACCINES AGAINST CHALLENGE OF FOALS WITH EQUINE HERPESVIRUS-1 - C.C. Breathnach
• LIVE ATTENUATED SALMONELLAE AS CARRIERS IN THE CONSTRUCTION OF ORAL MULTIVALENT VACCINES FOR DOGS - Jose A. Chabalgoity
• CLONING AND EXPRESSION OF CHROMOSOMAL DNA OF VACCINE STRAIN STI OF B. ANTHRACIS - N.N. Kislichkin
• PROTECTION STUDIES FOLLOWING BROCHOPULMUNARY AND INTRAMUSCULAR IMMUNIZATION WITH YERSINIA PESTIS RECOMBINANT SUBUNIT VACCINES ENTRAPPED IN BIODEGRADABLE MICROPARTICLES - J.E. Eyles
• NON-INVASIVE IMMUNIZATION STRATEGIES FOR PLAGUE - H.O. Alpar
• DEVELOPMENT OF AN IMMUNOTHERAPEUTIC VACCINE STRATEGY TO BVPASS THE T-HELPER CELL DEFECT IN HIV-1 INFECTED PERSONS AND GENERATE SYSTEMIC AND MUCOSAL IMMUNE RESPONSES - Basil Golding
• AUTOVACCINES AS THERAPEUTIC INSTRUMENTS TO TREAT CHRONIC BACTERIAL INFECTIONS - O. Nolte
• A GROUP B COXSACKIEVIRUS IS ATTENUATED BV SITE-SPECIFIC MUTATIONS WITHIN A COMPLETELY CONSERVED 5 NUCLEOTIDE SEQUENCE IN THE 5' NON-TRANSLATED REGION - S. Willian
• APPLICATION OF BIOINFORMATICS AND PROTEOMICS FOR IDENTIFICATION OF BACTERIAL GENE PRODUCTS AS POTENTIAL VACCINE CANDIDATES - Deb N. Chakravarti
• HARE: AN IMPROVED MEASURE OF EFFICACY FOR PHASE III HIV-l VACCINE TRIALS - K. Desai
• RATES OF MEDICALLY ATTENDED INJECTION SITE REACTIONS ASSOCIATED WITH ADULT VACCINATIONS - M.M. Braun
• SAFETY AND TOLERABILITY OF VARYING DOSES OF INFLUENZA VACCINE ADMINISTERED BY JET INJECTOR (JI) VS. NEEDLE AND SYRINGE (N&S) - L.A. Jackson
• PREDICTING THE NEUROVIRULENCE POTENTIAL OF MUMPS VIRUS VACCINE STRAINS FOR THE HUMAN CNS - S.A. Rubin
• EDIBLE VACCINE AGAINST HBC FROM TRANSGENIC PLANTS - L. Richter
• INDUCTION OF POTENT MUCOSAL ANTIBODY RESPONSES IN THE COMMON MUCOSAL IMMUNE SYSTEM BY RSV ICOMS AND RSV/GP120 ICOMS - Ke-Fei Hu
• INTRANASAL VACCINATION OF MICE WITH ROTAVIRUS VP6 AND LT(RI92G) INDUCED PROTECTION AGAINST INFECTION BV AN ANTIBODV- AND B-CELL INDEPENDENT MECHANISM A.H. - C. Choi
• USE OF THE SHIGELLA INVASIN COMPLEX AS A NEW SUBUNIT VACCINE AND MUCOSAL ADJUVANT - E.V. Oaks
• SKIN ADMINISTRATION OF POWDERED VACCINES IS A SAFE AND EFFECTVE WAV OF VACCINATION - D. Chen
• EVALUATION OF HUMAN CELLULAR IMMUNE RESPONSES AGAlNST HEPATITIS B FOLLOWING PARTICLE-MEDIATED EPIDERMAL DNA DELIVERY - Deborah Fuller
• PARTICLE-BASED INTRACELLULAR CO-DELIVERY OF DNA WITH A SAPONIN TYPE ADJUVANT ENHANCES SPECIFIC CELLULAR IMMUNE RESPONSES IN MICETH1 TYPE CYTOKINES, IN PARTICULAR IL-12 CONJECTION DRIVES ANTIGEN-SPECIFIC TH1 TYPE CD4+ T CELLS, RESULTING IN ENHANCED PROTECTION FROM LETHAL HERPES SIMPLEX VIRUS (HSV)- 2 CHALLENGE - J.-I. Sin
• THE IMPORTANCE OF IL-12 IN PROTECTIVE IMMUNITY AND IMMUNIZATION AGAINST THE PROTOZOAN, LEISHMANIA CHAGASI - M.E. Wilson
• DTH RESPONSES OF MICE IMMUNIZED WITH RECOMBINANT PROTEINS USING TWO CHITOSAN-BASED ADJUVANTS - P.G. Seferian
• IN VIVO EXPRESSION AND IMMUNOADJUVANCY OF A MUTANT OF HEAT-LABILE ENTEROTOXIN OF ESCERICHIA COLI IN VACCINE AND VECTOR STRAINS OF VIBRIO CHOLERAE - E.T. Ryan
• THE BACTEROIDES FRAGILIS METALLOPROTEASE ENTEROTOXlN, FRAGILYSIN, IS A MUCOSAL ADJUVANT - R.R. Vines
• ANALYSES OF HOST RESPONSES RELEVANT TO MEASLES VIRUS-INDUCED IMMUNOSUPPRESSION - H. Okada

• INDUCTION OF IMMUNE RESPONSES IN INDIVIDUALS SERONEGATIVE FOR HIV-1 FOLLOWING ADMINISTRATION OF ENV/REV HIV-1 DNA VACCINES - J. Boyer
• PROTECTIVE ANTIBODY RESPONSES IN MAN BY A DNA VACCINE FOR HEPATITIS B - M. Roy
• IMMUNOGENICITY AND PROTECTIVE EFFICAY OF A DENGUE VIRUS TYPE 1 DNA VACCINE IN A NON HUMAN PRIMATE MODEL - K. Raviprakash
• THE EFFECT OF DIFFERENT PROMOTERS AND ADJUVANTS FOR INTRAMUSCULARLY INJECTED DNA VACCINES IN CHICKENS - David Suarez