NFID

Foodborne Disease

Clinical Features

  • More than 250 foodborne diseases have been described.
  • Symptoms vary widely depending on etiologic agent.
  • Diarrhea and vomiting are most common.

Etiologic Agent

Many different bacteria (such as Campylobacter, Salmonella, and E. coli O157:H7), viruses, and parasites (such as Giardia), as well as natural and man-made chemicals (such as mushroom poison and heavy metals)

Incidence

Unknown. Estimates range from a minimum of 6 million to more than 80 million infections and intoxications/year in the U.S.

Sequelae

Septicemia, abortion, localized infections, arthritis, hemolytic uremic syndrome, paralysis, death.

Costs

Unknown. Medical costs and lost wages due to foodborne salmonellosis, only 1 of many foodborne infections, have been estimated to be more than $1 billion/year.

Transmission

  • Ingestion of contaminated food.
  • Person-to-person spread by fecal-oral route a major magnifier for some foodborne diseases.

Risk Groups

  • All persons.
  • Infants, elderly, and immunocompromised at increased risk of serious illness and death.

Surveillance

  • Foodborne Disease Outbreak Surveillance System (voluntary, passive, insensitive, and delayed).
  • Laboratory-based surveillance for some foodborne pathogens (e.g., Salmonella and Campylobacter).
  • Population-based studies of sporadic cases of specific foodborne diseases (e.g., listeriosis).
  • Active Foodborne Disease Surveillance for laboratory diagnosed infections in 5 sentinel areas with population of 11.2 million began in 1996.

Trends

  • Incidence of reported outbreaks has not changed in the last decade.
  • Re-emergence of old foodborne diseases (e.g., salmonellosis from pet reptiles).
  • Some diseases newly recognized as foodborne (e.g., listeriosis, hemolytic uremic syndrome).
  • Increasing resistance of foodborne pathogens to antimicrobial agents.

Challenges

  • Identify new foodborne pathogens.
  • Define points of intervention.
  • Implement and evaluate control strategies.

Opportunities

Identification of control points provides opportunity to directly intervene in the transmission of specific foodborne pathogens

Research Priorities

  • Improve assessment tools by developing active surveillance and improved diagnostic methods.
  • Quantify importance of specific products, processes, and behaviors.

March 1996
Courtesy of the Centers for Disease Control and Prevention